High-throughput screening (HTS) is an established method in drug discovery by which hundreds of thousands of compounds are screened in an automated fashion for activity as inhibitors or activators of ...

Developing new pharmaceuticals is a complex and costly process that requires innovation and efficiency. High-throughput immunoassays (HTIs) are an emerging technology poised to accelerate the drug ...

(A) Homogenous time-resolved fluorescence (HTRF) assay screening schematic. (B) HTRF assay screening compounds. (C) HTRF assay showed that the effect of FX1, BI-3802, and YK01 blocked the interaction ...

Deubiquitylating enzymes (DUBs) detach small ubiquitin modifications from protein substrates in eukaryotic cells. DUBs regulate many aspects of cell biology such as cell cycle progression, cell ...

The utilization of 3D organoids is increasingly prevalent in disease modeling and drug discovery due to their ability to better represent biologically relevant tissue architecture, microenvironments, ...