T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Mitochondrial calcium signalling plays a fundamental role in cellular homeostasis by modulating energy production and activating key metabolic enzymes. Calcium ions (Ca2+) are dynamically exchanged ...

Researchers have identified a specific hormone produced by pancreatic beta cells as a direct driver of obesity-linked pancreatic cancer in mouse models, shifting scientific attention away from insulin ...

A lipid hidden within cells called phosphatidylserine reveals how the body initiates the removal of threats and cellular ...