Roche has put forward a new approach to genetic analysis, which it describes as sequencing-by-expansion—a proprietary method that pulls apart the DNA molecule and amplifies the signal of each ...

DNA sequencing is a set of laboratory methods for determining the precise linear order of nucleotides (A, C, G, T) in a DNA molecule. Core methodological classes include Sanger sequencing, which uses ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

The presence or absence of remaining foreign DNA from the crossbred progeny of the genome-edited crop and the original crop cultivar can be determined by GenEditScan, based on the k-mer method.

A team including researchers at the University of California, Santa Cruz, has received a major grant from the National Human Genome Research Institute (NHGRI) to develop new technology for genome ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

LINE-1 retrotransposons are mobile genome parasites that drive cancer evolution by reshuffling the host genome.

A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, ...

A hot potato: Next-generation DNA sequencing (NGS) faces mounting scrutiny over its cyber vulnerabilities. While NGS has revolutionized fields ranging from cancer diagnostics to infectious disease ...