Enzymes are biological molecules that play a crucial role in various biochemical reactions within living organisms. They act as catalysts, which means they speed up the rate of chemical reactions ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life—how enzymes are able ...

Small-scale interactions of substrates with an enzyme's active site — over distances smaller than the length of a chemical bond — can make big differences to the enzyme's catalytic efficiency. Any ...

COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found. COX-1 and COX-2 ...

A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...

Enzymes catalyze the critical chemical reactions that help build and power living organisms. But chemists studying the origin of life on Earth face a vexing question: How did these metabolic reactions ...

For the first time, researchers have successfully used computational simulations to modify an enzyme’s structure to increase the optimum temperature of a reaction. Researchers at Uppsala University ...

The ensemble-function approach provides a quantitative catalytic model for serine proteases and identifies repeatedly evolved catalytic strategies. Credit: Science (2025). DOI: 10.1126/science.ado5068 ...