A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act ...

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...

The first steps following gene discovery have become somewhat routine: completing sequencing of the gene, matching the sequence to a known protein pattern (if possible), deciphering gene expression ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A ...

It often involves the introduction of genetic material into a person’s cells to replace a defective or missing gene. Although early attempts at gene therapy have been effective in achieving the ...

Scientists mapped hidden DNA switches in brain support cells to understand how gene control may influence Alzheimer’s disease ...

A synthetic PAS (red) is inserted in the 5′ UTR of a transgene. Without ligand, the cleavage destroys the coding region of the mRNA, therefore, losing transgene expression. Ligand binding to the ...