MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

From epic poetry to game shows, from Stone Age axes to spaceflight, humans have the most complex cultures of any species on Earth. Since the time of Darwin, scientists have suspected that this culture ...

Researchers at the University of Maine are theorizing that human beings may be in the midst of a major evolutionary shift—driven not by genes, but by culture. "Human evolution seems to be changing ...

A new Yale study provides a fuller picture of the genetic changes that shaped the evolution of the human brain, and how the process differed from the evolution of chimpanzees. For the study, published ...

It is often assumed that modern humans are no longer evolving. But there is now considerable agreement among scientists that evolution is still affecting our species—and this process is taking place ...

The genetic code acts as life’s instruction manual, telling cells how to build proteins from DNA and RNA. Though it's a marvel of molecular precision, the path it took to evolve remains unclear. Fresh ...

The present theory offers a unified solution to three closely related evolutionary problems. (1) Why does an evolving population explore only a small fraction of the accessible pathways in genotype ...

Charles Darwin's theory of evolution generated scientific debate and discussion not only in Darwin's own time, but for decades afterward. In the latter part of the nineteenth century and the until the ...