Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...
A study from an international team of experts in veterinary medicine, human medicine and genomics provides the first ...
Researchers show two distinct MECP2 mutations in Rett syndrome elevate miRNA-126-3p, lowering ZO-1 and weakening blood-brain ...
New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to ...
A refined base-pair editor limits unintended neighboring DNA edits while maintaining strong correction of disease-causing ...
From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...
Traditional biochemical methods of studying human gene mutations are often laborious and costly. Now bioengineers at the University of California San Diego have developed a new simple approach to ...
International team uncovers gene mutations that cause rare and aggressive cancer in both cats and humans. Their findings ...
The DNA damage from ionizing radiation (IR) erupting from the Chernobyl nuclear disaster of 1986 is showing up in the ...
A man sits outside and holds a slim menthol cigarette between his fingers. Close-up with focus on the cigarette. The study provided a comprehensive examination of how lifestyle and environmental ...