The Desk

Cascade PBS launches Local Public as standalone streaming tech company

The company provides branded streaming app technology for PBS member stations across connected TVs, mobile devices and the ...
Everyday Health

Understanding the ‘C3’ in C3G: Your Guide to Monitoring Complement Activity

C3G and IC-MPGN can be difficult to diagnose because they are so rare and their symptoms are vague and nonspecific. A kidney biopsy is considered the gold standard and usually needed to confirm the ...
Semiconductor Engineering

How SW and HW Vulnerabilities Can Complement LLM-Specific Algorithmic Attacks (UT Austin, Intel et al.)

A new technical paper, “Cascade: Composing Software-Hardware Attack Gadgets for Adversarial Threat Amplification in Compound AI Systems,” was published by the University of Texas, Austin, Intel Labs, ...
Phys.org

Quantum algorithm beats classical tools on complement sampling tasks

Quantum computers—devices that process information using quantum mechanical effects—have long been expected to outperform classical systems on certain tasks. Over the past few decades, researchers ...
The Register-Guard

Bi-Mart to close all Cascade Farm and Outdoor locations this spring

Bi-Mart announced Jan. 27 the company will close its five Cascade Farm and Outdoor locations this spring to focus on Bi-Mart’s expansion efforts in the Pacific Northwest. According to a press release, ...
Smithsonian Magazine

Women Are More Likely to Have Irritable Bowel Syndrome. This Newfound Gut Pain Pathway Might Explain Why

Estrogen may cause certain colon cells, shown in green in this microscope image, to release a hormone called peptide YY. This, in turn, causes a different type of colon cell, colored magenta, to pump ...
ALZFORUM

Brain Injury Swells Ranks of Complement-Primed Microglia

Scientists have spotted a new variety of riled-up microglia that drives swelling in the human brain. In the November 18 Neuron, researchers from China led by Haixiao Liu, Shunnan Ge, and Yan Qu at ...
ALZFORUM

TDP-43 Knockdown Kicks Off a Cascade of Protein Changes

In amyotrophic lateral sclerosis and frontotemporal dementia, loss of nuclear TDP-43 mucks up splicing of many transcripts, squelching expression of the associated proteins. However, this missplicing ...
ophthalmologytimes

FDA clears IND for Complement Therapeutics’ CTx001 gene therapy in geographic atrophy

FDA approval enables Complement Therapeutics to start the Opti-GAIN phase 1/2 trial for CTx001 in GA secondary to AMD. CTx001 is an AAV-based gene therapy delivering a truncated Complement Receptor 1 ...
Healthline

An Overview of Complement 3 Glomerulopathy (C3G)

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...
Business Wire

Cascade Bio Secures $6M to Scale Breakthrough Biocatalysts

DENVER--(BUSINESS WIRE)--Cascade Bio, an industrial biotech company enabling enzyme-based processes, has secured $6M to accelerate the shift from petrochemicals to biomanufacturing. The funding ...