Background Patients with heart failure (HF) frequently suffer from undetected declines in cardiorespiratory fitness (CRF), which significantly increases their risk of poor outcomes. However, current ...

Philip McKibbin does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...

A woman suffers a heart attack because of an undiagnosed heart condition. Rather than asking her to trial different drugs to find the best one for ongoing treatment, doctors instead generate a digital ...

Emma.me isn’t pretending. She’s just knocked out the training wheels of girlhood and is running wild with the adrenaline of “adulthood” in name only. Cry-laugh emojis everywhere. This is the digital ...

This study presents valuable findings implicating nuclear export in the regulation of protein condensate behaviour and TDP-43 phase behaviour, suggesting a link to pathogenic aggregation in ALS/FTD.