The FDA is raising the bar for approval of CAR T-cell therapies in oncology. Under plans outlined by the FDA’s biologics chief Vinay Prasad, M.D., the agency will require developers of many CAR-Ts to ...

Abstract: Safety and data efficiency are important concerns in data-driven control, especially for nonlinear systems with unknown dynamics and subject to disturbances. In this work, we consider a ...

Methods: A 12-week, parallel, single-blind randomized controlled trial was conducted with 123 participants (62/123, 50%, female; mean age 58.25 years, SD 9.46 years) recently diagnosed with T2D.

What policies and programs can society implement to make a tangible, lasting impact on people’s lives? Social scientists have been trying to answer this question for decades by conducting randomized ...

Malaria causes about 1/4 billion new cases of disease and about 600,000 deaths every year. 3/4 of the deaths are children under 5 years old. The July 23, 2025, NEJM has a free full text article ...

Objective: This study aims to determine whether the use of a digital diabetes logbook increased the likelihood of achieving optimal glycemic control (glycated hemoglobin [HbA1c] ≤6.5%) after 3 months, ...

1 Faculty of Educational Sciences, Department of Special Needs Education, University of Oslo, Oslo, Norway 2 Knowledge Centre for Education, University of Stavanger, Stavanger, Norway Introduction: ...

Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic ...