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see what happen to your brain when you abuse drugs
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TikTokourcrazylife1997
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GABA!!! Two big distinctions here— positive allosteric modulators (benzos) vs direct agonists (anesthetics like propofol or alfaxalone). Disinhibitions occurs because downstream neurons are not receiving inhibitory signals anymore (because that presynaptic neuron is inhibited by our drug while normally it releases GABA to calm downstream neurons). neuropharm is so juicy. #fyp #gaba #vetmed
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TikTokbexie
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🦷 There’s a reason the countdown always wins. General anesthetics work by binding to GABA receptors in the brain, the same system responsible for slowing down neural activity, which forces neurons across the cortex to quiet at once and triggers loss of consciousness within seconds. Researchers at MIT recently described it as the brain losing “dynamic stability,” meaning no amount of willpower or focus can override it once the drug reaches the bloodstream. Even seasoned anesthesiologists say the
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